BioinformaticsPLoS Computational BiologyPeer-reviewed
Ancestral Haplotype Reconstruction in Endogamous Populations using Identity-By-Descent
Kelly Finke, Michael Κourakos, Gabriela Brown…·Sara Mathieson
This paper introduces an algorithm called thread to reconstruct ancestral haplotypes in endogamous populations using pedigree and genotype data, finding it can reconstruct 79% of haplotypes for 224 ancestral individuals per chromosome.
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