Author

David P. Astling

University of Colorado AnschutzORCID 0000-0001-8179-0304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

An StaesiD· 1 shared Audrey E. HendricksiD· 1 shared Beat VögeliiD· 1 shared Benedikt HallgrímssoniD· 1 shared Feyza YilmaziD· 1 shared Frans M. Van RoyiD· 1 shared Hung‐Chun YuiD· 1 shared James M. SikelaiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

An StaesORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 21, 2024

Olduvai domains downregulate mitochondrial pathways to promote human brain evolution and neoteny

Jonathon Keeney, David P. Astling, Vanessa Andries…·James M. Sikela

This study shows Olduvai domains suppress mitochondrial pathways, delaying cellular maturation and promoting brain size increase in humans.

3 citations

humanproteomics

𝕏 PostBluesky

GenomicsBMC Medical GenomicsPeer-reviewedMay 17, 2021

Genome-wide Copy Number Variations in a Large Cohort of Bantu African Children

Feyza Yilmaz, Megan Null, David P. Astling…·Tamim H. Shaikh

This study identifies over 400,000 CNVs in 3400 Bantu African children, highlighting common CNVs overlapping disease-associated genes and providing a large dataset for African ancestry CNV research.

11 citations

humanwhole-genome sequencing

𝕏 PostBluesky