Evolutionary BiologybioRxivPreprint
Can you trust your reconstructed lineage tree? A homoplasy-based approach for irreversible evolution
Pini Zilber, Sebastian Prillo, Yaara Neumeier…·Boaz Nadler
This paper introduces a homoplasy-based method to assess lineage tree reliability using Cas9-induced mutations, showing it outperforms parsimony in simulations.
DOI 10.1101/2025.07.27.667007