Author

Kimme Leanne Hyrich

Manchester Academic Health Science CentreORCID 0000-0001-8242-9262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan M RosenbergiD· 1 shared Carl D. LangefeldiD· 1 shared Carol A. WiseiD· 1 shared Ekaterina S KhvatkovaiD· 1 shared Ellen Berit NordaliD· 1 shared Grant S. SchulertiD· 1 shared Hannah C. AinsworthiD· 1 shared James N. JarvisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alan M RosenbergORCID

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1 paper

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintSep 17, 2026

Identification and evaluation of 41 risk loci for juvenile idiopathic arthritis informs precision medicine: mechanistic implications of DNA topology and an HLA-A*02:01-ERAP2 interaction

Hannah C. Ainsworth, Ekaterina S Khvatkova, Marc Sudman…·Carl D. Langefeld

This paper identifies 41 risk loci for juvenile idiopathic arthritis, including 14 novel ones, and presents a polygenic risk score associated with age of onset, along with functional mechanisms involving DNA topology and an HLA-A*02:01-ERAP2 interaction.

DOI 10.64898/2026.09.16.26363161

humanGWAS summary statistics

𝕏 PostBluesky