Hannah C. Ainsworth

This study profiles B cell activation states using multi-omics data to identify genetic mechanisms underlying immune-mediated diseases.

This paper identifies 41 risk loci for juvenile idiopathic arthritis, including 14 novel ones, and presents a polygenic risk score associated with age of onset, along with functional mechanisms involving DNA topology and an HLA-A*02:01-ERAP2 interaction.

The paper develops a web-based tool to estimate sample sizes for non-human primate longitudinal studies using natural healthspan data.

This study shows that unacylated ghrelin prevents muscle and mitochondrial dysfunction in cancer cachexia by improving muscle mass, mitochondrial function, and reducing proteolysis.

This study computes sex-specific survival curves for 12 nonhuman primate species to characterize aging patterns and provides insights into lifespan and healthspan differences.

This study introduces DNA topology as a prioritization metric for genomic fine-mapping, using minor groove width changes to identify functionally relevant SNPs in non-coding regions associated with System Lupus Erythematosus.