BioinformaticsJournal of Molecular Graphics and ModellingPeer-reviewed
E484K mutation in SARS-CoV-2 RBD enhances binding affinity with hACE2 but reduces interactions with neutralizing antibodies and nanobodies: Binding free energy calculation studies
Wei Bu Wang, Yu Liang, Yu Qin Jin…·Qi Ming Li
This study investigates how the E484K mutation in SARS-CoV-2 RBD affects binding to hACE2 and neutralizing antibodies using molecular dynamics simulations.
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