Brain morphological pattern is associated with the presence, severity, and transition of transdiagnostic psychiatric disorders in preadolescents
Nanyu Kuang, Christopher Joseph Hammond, Betty Jo Salmeron, Xiang Xiao, Danni Wang, Laura Murray, Hong Gu, Tianye Zhai, Hui Zheng, Justine Hill, Maria K. Scavnicky, Hanbing Lu, Amy C. Janes, Thomas J. Ross, Yihong Yang
In 8,672 ABCD preadolescents, one canonical-correlation-derived brain morphology variate links higher cognition with lower psychopathology and tracks cumulative psychiatric diagnoses and 2-year diagnostic transitions.
Nature Mental Health · Aug 20, 2026Peer-reviewedDevelopmental Biology✦ In-depth digest