Yihong Yang

Focal Transcranial Magnetic Stimulation of the Rat Anterior Cingulate Cortex Inhibits Incubation of Opioid Craving after Voluntary Abstinence

Focal transcranial magnetic stimulation of the rat anterior cingulate cortex reduced relapse-like behavior and restored corticostriatal connectivity during opioid abstinence.

Brain morphological pattern is associated with the presence, severity, and transition of transdiagnostic psychiatric disorders in preadolescents

In 8,672 ABCD preadolescents, one canonical-correlation-derived brain morphology variate links higher cognition with lower psychopathology and tracks cumulative psychiatric diagnoses and 2-year diagnostic transitions.

High-density theta burst stimulation (hdTBS) at 100 Hz triples the aftereffects of the conventional intermittent TBS

This paper introduces a new TMS paradigm, 100 Hz hdTBS, which triples the aftereffects of conventional iTBS in rats, highlighting the importance of pulse timing over total pulse count.

Physiological Arousal as a Predominant Source of Individual Differences in Functional Brain Networks

This paper identifies physiological arousal as a major source of individual differences in functional brain networks, showing strong correlations between arousal and network properties across multiple sessions and samples.

A cell type-specific mechanism driving the rapid antidepressant effects of transcranial magnetic stimulation

This study identifies a cell type-specific mechanism in the prefrontal cortex that underlies the rapid antidepressant effects of a specific rTMS protocol in a mouse model.

Maturation of Dorsal Association Tracts during Preadolescence Links to Concurrent and Future Cognitive Performance and Transdiagnostic Psychopathology

This study links WM maturation in preadolescence to cognitive performance and future psychiatric disorders using normative models of brain age.

Targeted medial prefrontal cortex stimulation prevents incubation of cocaine craving and restores functional connectivity

Focal transcranial magnetic stimulation of the medial prefrontal cortex prevents cocaine craving incubation and restores functional connectivity in a rat model of relapse.

Multidimensional MRI reveals cellular-scale microstructural phenotypes in human brain aging

This study uses multidimensional MRI to analyze cellular-scale microstructural changes in the human brain across aging, revealing increased heterogeneity and loss of microscopic restriction.

Predicting individual incubation of opioid craving by whole-brain functional connectivity

The paper identifies a whole-brain functional connectivity pattern that predicts individual differences in opioid craving incubation in rats after abstinence.

Comorbid HIV and Cocaine Use Exacerbate Accelerated Brain Aging

This study finds that comorbid HIV and cocaine use are associated with accelerated brain aging and increased cognitive impairment, with the greatest effects seen in individuals with both conditions.

Functional MRI reveals regional changes of brain activity after five days of focal high-density theta burst stimulation (hdTBS) of the rat brain

This study develops a rat model of high-density theta burst stimulation (hdTBS) and shows it increases cortical excitability and basal cerebral blood volume in specific brain regions.

In vivo disentanglement of diffusion frequency-dependence, tensor shape, and relaxation using multidimensional MRI

This paper introduces an efficient in vivo MD-MRI protocol for whole-brain imaging and demonstrates its feasibility and robustness using phantoms and human scans.

Personalized connectivity-based network targeting model of TMS for treatment of psychiatric disorders: computational feasibility and reproducibility

This study evaluates a personalized network targeting model for TMS in psychiatric disorders using rsfMRI data, finding that 28-minute scans and clustering improve site identification stability.

The variability of multidimensional diffusion-relaxation MRI estimates in the human brain

This paper evaluates the reliability and reproducibility of multidimensional diffusion-relaxation MRI (MD-MRI) in the human brain, showing it can reliably capture structural and chemical diversity within voxels.

Role of ventral subiculum neuronal ensembles in incubation of oxycodone craving after electric barrier-induced voluntary abstinence

This study shows that ventral subiculum neuronal ensembles are specifically involved in the incubation of oxycodone craving after voluntary abstinence, but not after forced abstinence or early abstinence.

Targeting the pathological network: feasibility of network-based optimization of transcranial magnetic stimulation coil placement for treatment of psychiatric disorders

This study proposes and validates a network-based model for optimizing TMS coil placement in psychiatric disorders by targeting disease-specific brain networks.

Angle-Tuned Coils: Enabling Building Blocks for High Performance and Multisite TMS Systems

This paper introduces angle-tuned TMS coils that improve depth-spread tradeoff and enable multisite brain stimulation with reduced footprint and field spread.

Supramammillary neurons projecting to the septum regulate dopamine and motivation for environmental interaction

This study identifies a pathway involving supramammillary neurons projecting to the septum that regulates dopamine and motivation for environmental interaction in mice.

Higher-order sensorimotor circuit of the brain' global network supports human consciousness

The paper identifies higher-order sensorimotor brain hubs that correlate with consciousness levels across different unconscious states using resting-state fMRI data.

Medial Prefrontal Cortex Interacts with the Anteromedial Thalamus in Motivation and Dopaminergic Activity

The paper identifies a cortico-thalamic loop between the medial prefrontal cortex and anteromedial thalamus that regulates motivation, reinforcement, and dopaminergic activity through reciprocal connectivity and feedback.

Anterior insular cortex plays a critical role in interoceptive attention

This study demonstrates that the anterior insular cortex is critical for interoceptive attention by showing its activation and connectivity patterns in healthy individuals and impaired function in patients with AIC lesions.

Do Candidate Genes Affect the Brain’s White Matter Microstructure? Large-Scale Evaluation of 6,165 Diffusion MRI Scans

The paper evaluates 15 candidate SNPs associated with psychiatric disorders using 6,165 diffusion MRI scans, finding no significant associations after correction for multiple testing.