Zhifeng Gao

CycDelta is a multimodal residue-graph model for predicting permeability changes in cyclic peptides by comparing within-source permeability differences, outperforming baselines on out-of-distribution and zero-shot tasks.

Uni-Clip improves protein-ligand interaction modeling for undruggable and druggable targets using multimodal contrastive learning, showing significant performance gains in benchmark datasets.