Author

Joseph L. Graves

North Carolina Agricultural and Technical State UniversityORCID 0000-0001-8446-1709Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Checo J. RorieiD· 2 shared Dipongkor SahaiD· 2 shared Md. IftehimuliD· 2 shared Misty D. ThomasiD· 2 shared Muhammad T. Hossain· 2 shared Perpetua M. MugandaiD· 2 shared Robert Howard NewmaniD· 2 shared Scott Henry HarrisoniD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Checo J. RorieORCID

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2 papers

Recent·Most cited

Molecular Plasticity of T Cells Informs Their Possible Adaptation in 4T1 Tumors

Md. Iftehimul, Robert Howard Newman, Scott Henry Harrison, Roshonda B. Jones, Perpetua M. Muganda, Bryan Latrell Holloman, Muhammad T. Hossain, Checo J. Rorie, Misty D. Thomas, Joseph L. Graves, Howard L. Kaufman, Dipongkor Saha

This study tracks T cell transcriptional changes in 4T1 tumors over time, revealing functional decline, reduced TCR diversity, and immunosuppressive shifts in the tumor microenvironment.

bioRxiv · Oct 17, 2025 · PreprintCancer Biology

Molecular Phenotypic Plasticity Informs Possible Adaptive Change of Triple-Negative Breast Cancer Cells In Vivo

Md. Iftehimul, Perpetua M. Muganda, Robert Howard Newman, Checo J. Rorie, Scott Henry Harrison, Muhammad T. Hossain, Misty D. Thomas, Joseph L. Graves, Dipongkor Saha

This study examines in vivo gene expression changes in triple-negative breast cancer cells over time, revealing early transcriptional shifts and significant molecular reprogramming linked to ecDNA alterations and immune evasion.

bioRxiv · May 31, 2025 · PreprintCancer Biology