BioinformaticsNature CommunicationsPeer-reviewed
Sparse Epistatic Regularization of Deep Neural Networks for Inferring Fitness Functions
Amirali Aghazadeh, Hunter M. Nisonoff, Orhan Öçal…·Kannan Ramchandran
This paper introduces a method to improve deep neural network predictions of fitness functions by leveraging sparse epistatic interactions in genetic sequences.
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