GeneticsbioRxivPreprint
Drop of Prevalence after Population Expansion: A lower prevalence for recessive disorders in a random mating population is a transient phenomenon during and after a growth phase
Luis A. La Rocca, Julia Frank, Heidi Beate Bentzen…·Peter Michael Krawitz
The paper models how population expansion affects recessive disorder prevalence and mutation load, showing that random mating leads to a temporary decrease in disease incidence but increased mutation load.
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