Author

Bernard Chazelle

Princeton UniversityORCID 0000-0001-8542-0247Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

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Mona SinghiD· 1 shared Shilpa N. KobreniD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBioinformatics

Mona SinghORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintAug 13, 2019

An integrative approach uncovers genes with perturbed interactions in cancers

Shilpa N. Kobren, Bernard Chazelle, Mona Singh

The paper introduces PertInInt, a method that identifies cancer genes by analyzing somatic mutations in interaction sites across 10,037 tumor samples, revealing disrupted interactions as a common cancer mechanism.

DOI 10.1101/733485

humanwhole-exome sequencing

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