Quantitative Modelling of Amyloid-β Dynamics in Brain, CSF, and Plasma During Sleep and Wakefulness
Satyam Sangeet, Craig L. Phillips, Camilla M. Hoyos, Angela L. D'Rozario, Brendan P. Lucey, Svetlana Postnova
The paper models A{beta} dynamics across brain, CSF, and plasma during sleep and wakefulness, showing increased CSF A{beta}42 levels after sleep due to sampling effects and impaired clearance.
bioRxiv · Sep 14, 2026 · PreprintNeuroscience