Satyam Sangeet

Quantitative Modelling of Amyloid-β Dynamics in Brain, CSF, and Plasma During Sleep and Wakefulness

The paper models A{beta} dynamics across brain, CSF, and plasma during sleep and wakefulness, showing increased CSF A{beta}42 levels after sleep due to sampling effects and impaired clearance.

EVOLVE: A Web Platform for Evolutionary Phase Analysis and New Variant Exploration from Multi-Sequence Data

EVOLVE is a web platform that analyzes multi-sequence data to identify concerning variants using phase transition principles and provides tools for exploring mutational metrics.

Bacopa monnieri phytochemicals as promising BACE1 inhibitors for Alzheimers Disease Therapy

This study evaluates Bacopa monnieri phytochemicals as BACE1 inhibitors for Alzheimer's disease, showing superior binding affinity and introducing a visualization platform for protein-ligand interactions.

Machine Learning-Enhanced Drug Discovery for BACE1: A Novel Approach to Alzheimer's Therapeutics

This study uses machine learning to design novel BACE1 inhibitors with improved binding affinity and mechanism of action compared to existing drugs.

Small molecules from Bacopa monneiri as potent inhibitors against Neurodegenerative disorders

The paper evaluates the pharmacological effects of Bacopa monnieri phytochemicals using in-silico methods to identify potential inhibitors of amyloid-β plaques.