Alberto Pessia

SynergyFinder Plus improves interpretation and annotation of drug combination screening data through updated methods and a web interface.

The paper introduces the drda R package for dose-response data analysis, offering improved accuracy through optimized least-squares methods and demonstrates its performance on a drug sensitivity dataset.

The paper improves gene essentiality consistency between RNAi and CRISPR screens by integrating molecular features, resulting in a more accurate combined essentiality score.