Author

Jian‐Huan Chen

Jiangnan UniversityORCID 0000-0001-8714-2543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jiaqi Pan· 3 shared Xubin PaniD· 2 shared Yanshan LiuiD· 2 shared Yunyun JiniD· 2 shared Chunyan ReniD· 1 shared En‐Min LiiD· 1 shared Jiali ZhangiD· 1 shared Jifeng Wan· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Jiaqi Pan

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3 papers

Recent·Most cited

Molecular BiologyLife SciencesPeer-reviewedSep 24, 2026

Paraspeckles translate microbial insult-induced inflammation into neurovascular remodeling by enhancing CYR61-FGF2 signaling via RBM14 sequestration

Jiaqi Pan, Kai-Tong Yang, Jing-Qian Zhang…·Jian‐Huan Chen

The paper identifies paraspeckles as mediators of microbial insult-induced neurovascular remodeling through CYR61-FGF2 signaling via RBM14 sequestration, showing therapeutic potential.

DOI 10.1016/j.lfs.2026.124708

mousehuman

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GenomicsbioRxivPreprintFeb 21, 2024

Multi-tissue transition of A-to-I RNA editing pattern and its regulatory relevance in transcription, splicing, and translation during development

Jiaqi Pan, Xubin Pan, Yanshan Liu…·Jian‐Huan Chen

The paper analyzes A-to-I RNA editing dynamics across six mouse tissues during development, showing increased editing activity and its impact on gene expression and splicing.

DOI 10.1101/2024.02.21.581478

mousebulk RNA-seq

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GeneticsbioRxivPreprintMay 22, 2020

Novel missense mutation E585K in retinitis pigmentosa leads to compromised RPGR splicing diversity

Yanshan Liu, Jifeng Wan, Chunyan Ren…·Jian‐Huan Chen

The paper identifies a novel missense mutation E585K in RPGR that affects RNA splicing patterns, leading to reduced splicing diversity and potentially explaining slow disease progression in RP patients.

DOI 10.1101/2020.05.22.109884

humanwhole-exome sequencing

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