Author

Samuel L. Bruce

Columbia UniversityORCID 0000-0001-8755-5081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine A. SchevoniD· 1 shared Elliot H. SmithiD· 1 shared Eve ByingtoniD· 1 shared Guy M. McKhanniD· 1 shared Haicang ZhangiD· 1 shared Jyun-you LiouiD· 1 shared Larry F. AbbottiD· 1 shared Lisa M. BatemaniD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Catherine A. SchevonORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 15, 2020

Dissecting Autism Genetic Risk Using Single-cell RNA-seq Data

Siying Chen, Xueya Zhou, Eve Byington…·Yufeng Shen

The paper uses single-cell RNA-seq data to develop a machine learning method called A-risk to prioritize autism risk genes, identifying 71 candidates including new ones like CLCN4, PRKAR1B, and NR2F1.

6 citations

humanscRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 3, 2019

A theoretical model for focal seizure initiation, propagation, termination, and progression

Jyun-you Liou, Elliot H. Smith, Lisa M. Bateman…·Larry F. Abbott

The paper develops a neural network model to simulate focal seizure dynamics, including initiation, propagation, termination, and progression, and identifies mechanisms underlying seizure patterns and synaptic plasticity.

2 citations

statistical model

𝕏 PostBluesky