Author

Leonardo Di Gennaro

Agostino Gemelli University PolyclinicORCID 0000-0001-8762-0920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Antonietta FerrettiiD· 1 shared Giancarlo CastamaniD· 1 shared Maria Basso· 1 shared Monica SaccoiD· 1 shared Raimondo DE CRISTOFAROiD· 1 shared Stefano LancellottiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Antonietta FerrettiORCID

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1 paper

Recent·Most cited

BiochemistryPLoS Computational BiologyPeer-reviewedDec 3, 2025

Natural variants of von Willebrand factor R1205 causing von Willebrand disease with accelerated von Willebrand factor clearance: in silico docking models and energetics of the interaction with both LRP1 and GpIb A1 domain

Monica Sacco, Stefano Lancellotti, Antonietta Ferretti…·Raimondo DE CRISTOFARO

The paper uses computational models to show how R1205 variants in von Willebrand factor alter interactions with LRP1 and GPIb, explaining disease mechanisms and offering therapeutic insights.

DOI 10.1371/journal.pcbi.1013458

humanprotein structure

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