Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewed
Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade
Jade Moore, Jim Gkantalis, Inés Guix…·Mary Helen Barcellos‐Hoff
This study identifies a biomarker, {beta}Alt, that predicts immune checkpoint blockade response in cold tumors by integrating TGF{beta} signaling, DNA repair, and immune context signatures.