Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade
Jade Moore, Jim Gkantalis, Inés Guix, William S. Chou, Kobe Chi Yung Yuen, Ann Lazar, Matthew H. Spitzer, Alexis J. Combes, Mary Helen Barcellos‐Hoff
This study identifies a biomarker, {beta}Alt, that predicts immune checkpoint blockade response in cold tumors by integrating TGF{beta} signaling, DNA repair, and immune context signatures.
Journal for ImmunoTherapy of Cancer · Mar 1, 2025Peer-reviewedCancer Biology