Author

Yanling Wu

Shanghai Medical College of Fudan UniversityORCID 0000-0001-8780-8640Unclaimed ORCID profile · follow to get notified of new preprints

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Yanling Wu1 paper · Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; Shanghai Engineering Research Center for Synthetic Immunology, Shanghai 200032, China;

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Approach:graph neural network· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Quanxiao LiiD· 2 shared Tianlei YingiD· 2 shared Bozitao ZhongiD· 1 shared Fandi WuiD· 1 shared Huiyu CaiiD· 1 shared Jiale Shi· 1 shared Jian TangiD· 1 shared Jianhua YaoiD· 1 shared

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2024-2025 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Quanxiao LiORCID

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2 papers

Recent·Most cited

BioinformaticsCell DiscoveryPeer-reviewedOct 29, 2025

A synergistic generative-ranking framework for tailored design of therapeutic single-domain antibodies

Yu Kong, Jiale Shi, Fandi Wu…·Tianlei Ying

This paper introduces TFDesign-sdAb, a deep learning framework for designing therapeutic single-domain antibodies with tailored functionalities, achieving high success rates in generating Protein A-binding sdAbs.

2 citations

humanprotein structure

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BioinformaticsNature CommunicationsPeer-reviewedSep 6, 2024

Pretrainable Geometric Graph Neural Network for Antibody Affinity Maturation

Huiyu Cai, Zuobai Zhang, Mingkai Wang…·Jian Tang

This paper introduces GearBind, a geometric graph neural network for in silico antibody affinity maturation, achieving significant improvements in binding affinity.

56 citationstop 1%

protein structuredeep learning

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