Author

Anthony J. Coyle

ORCID 0000-0001-8802-985XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:contrastive learning· 1 Organism:human· 1

Frequent Co-Authors

Brinda Vijaykumar· 1 shared Christophe O. BenoistiD· 1 shared Daniel C. PregiboniD· 1 shared John Abel· 1 shared Neel Patel· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Brinda Vijaykumar

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1 paper

Recent·Most cited

REPTRA: Mapping Immune T Cell Receptor Activity from Full Sequences with a Debiased Contrastive Loss

John Abel, Brinda Vijaykumar, Neel Patel, Anthony J. Coyle, Christophe O. Benoist, Daniel C. Pregibon

The paper introduces REPTRA, a contrastive learning model for TCR-epitope recognition using full TCR sequences and a debiased loss function, showing improved performance and highlighting the importance of CDR1 and CDR2.

bioRxiv · Oct 22, 2025 · PreprintImmunology