Shin Murakami

This study identifies age-related genes associated with leading causes of death by analyzing protein-protein interactions and gene set enrichment, finding 15 recurring genes linked to multiple diseases.

This study identifies 43 genes linked to centenarians and red wine consumption, highlighting their roles in stress response, apoptosis, and disease pathways associated with longevity.

This study identifies 541 human genes associated with stress resistance and finds overlapping and distinct pathways with longevity, including PIP3-AKT-FOXO and mTOR, but also notes inconsistencies in pathway terminology.

This study identifies shared genetic pathways between Alzheimer's disease, aging, and longevity using gene set enrichment analysis and validates them with statistical significance.

This paper performs a meta-analysis of ACE I/D polymorphisms in centenarians and long-lived individuals, finding a positive association of the DD genotype with longevity but not the ID genotype.