Unified Genomic and Chemical Representations Enable Bidirectional Bio-synthetic Gene Cluster and Natural Product Retrieval
Guimei Liu, Yiting Li, Gabriel Ong, Fong Tian Wong, Dillon W. P. Tay, Yee Hwee Lim, Chuan-Sheng Foo, Winston Lian Chye Koh
This paper introduces a multimodal framework that links biosynthetic gene clusters and natural products by integrating genomic and chemical data through shared embeddings, enabling bidirectional retrieval and strain selection.
Scientific Reports · May 9, 2026Peer-reviewedSynthetic Biology