Author

Edward M. Culbertson

University of PittsburghORCID 0000-0001-9016-3871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Benjamin R. MorehouseiD· 1 shared Emily Cruz-LorenzoiD· 1 shared Harshitha Gompa· 1 shared James R. DrureyiD· 1 shared Jeffrey J. LangeiD· 1 shared Jocelyn Leon PadillaiD· 1 shared Megan Halfmann· 1 shared Neha Garlapati· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

Benjamin R. MorehouseORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Eukaryotic domestication of a TIR bacterial immune protein following horizontal transfer

Edward M. Culbertson, Emily Cruz-Lorenzo, Jocelyn Leon Padilla, Megan Halfmann, James R. Drurey, Jeffrey J. Lange, Yao Li, Neha Garlapati, Harshitha Gompa, Benjamin R. Morehouse, Randal Halfmann, Tera C. Levin

This study identifies a horizontal transfer of a bacterial TIR immune protein to amoebae, showing how it was domesticated into eukaryotic physiology through functional adaptation.

bioRxiv · Oct 16, 2026 · PreprintMicrobiology