IL-17A primes an early progenitor compartment to tune the erythropoietic feedback circuit
Qiu Chang Wu, Aishwarya Swaminathan, Ashley Winward, Logan Lalonde, Yung Hwang, Noah Littman, Merav Socolovsky, Allon Moshe Klein
This study shows IL-17A enhances erythropoietic response to hypoxia by sensitizing progenitors to erythropoietin, balancing reactivity and steady-state burden.
bioRxiv · Dec 16, 2024 · PreprintSystems Biology