Cell BiologyBlood AdvancesPeer-reviewed
Epo and hypoxia accelerate a pattern of gradual cell cycle shortening in BFU-e and CFU-e erythroid progenitors in vivo
1 citation
Author
Merav Socolovsky
University of Massachusetts Chan Medical SchoolORCID 0000-0001-6747-7960Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2025 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 23 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- Systems BiologybioRxivPreprint
IL-17A primes an early progenitor compartment to tune the erythropoietic feedback circuit
Qiu Chang Wu, Aishwarya Swaminathan, Ashley Winward…·Allon Moshe Klein
This study shows IL-17A enhances erythropoietic response to hypoxia by sensitizing progenitors to erythropoietin, balancing reactivity and steady-state burden.
2 citations - Developmental BiologybioRxivPreprint
The Erythropoietin Receptor Stimulates Rapid Cycling and Formation of Larger Red Cells During Mouse and Human Erythropoiesis
Daniel Hidalgo, Jacob Bejder, Ramona Pop…·Merav Socolovsky
This study shows that EpoR signaling accelerates cell cycling and increases red cell size in mouse and human erythropoiesis, independent of HRI and not due to reticulocyte increase.
- GenomicsNature CommunicationsPeer-reviewed
Dynamics of the 4D genome during lineage specification, differentiation and maturation in vivo
A. Marieke Oudelaar, Robert A. Beagrie, Matthew E. Gosden…·Jim R. Hughes
The paper studies chromatin architecture changes during mouse erythroid differentiation using Tiled-C and shows enhancer-promoter interactions form during differentiation, not before gene expression.
- Systems BiologyProceedings of the National Academy of SciencesPeer-reviewed
Fundamental limits on dynamic inference from single cell snapshots
Caleb Weinreb, Samuel L. Wolock, Betsabeh Khoramian Tusi…·Allon Moshe Klein
This paper identifies fundamental limits on inferring gene expression dynamics from single-cell snapshots and introduces an algorithmic approach to constrain dynamic solutions.
- Systems BiologybioRxivPreprint
Emergence of the erythroid lineage from multipotent hematopoiesis
Betsabeh Khoramian Tusi, Samuel L. Wolock, Caleb Weinreb…·Merav Socolovsky
The paper uses single-cell transcriptomics and fate potential assays to map the erythroid differentiation trajectory from multipotent hematopoietic stem cells in mice, revealing novel regulators and transcriptional programs.