Primed to Die: An Investigation of the Genetic Mechanisms Underlying Noise-Induced Hearing Loss and Cochlear Damage in Homozygous Foxo3-knockout Mice
Holly J. Beaulac, Felicia A. Gilels, Jingyuan Zhang, Sarah Jeoung, Patricia M. White
This study investigates how FOXO3 protects cochlear cells from noise-induced damage in mice, finding that its absence leads to increased cell death and hearing loss, with LPA treatment offering partial protection.
Cell Death and Disease · Jul 7, 2021Peer-reviewedNeuroscience