Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
Daniel C. Morgan, Matthew Studham, Andreas Tjärnberg, Holger Weishaupt, Fredrik J. Swartling, Torbjörn E. M. Nordling, Erik L. L. Sonnhammer
The paper infers a gene regulatory network (GRN) from perturbation experiments in cancer cells, identifying both known and novel regulatory interactions that contribute to oncogenic processes.
Scientific Reports · Aug 25, 2020Peer-reviewedSystems Biology