Lars Magnus Valnes

The impact of human brain geometry on the transport of an intrathecal tracer

This study predicts tracer distribution in the brain using geometric MRI data, showing strong correlation with actual tracer enrichment in patients with similar diagnoses.

Numerical experiments for reconstructing cerebrospinal fluid flow based on contrast enhanced magnetic resonance images in the lower subarachnoid compartments of the brain

The paper tests numerical methods for reconstructing cerebrospinal fluid flow from contrast-enhanced MRI data, finding that methods perform well in idealized settings but struggle with patient-specific data.

CSF circulation and dispersion yield rapid clearancefrom intracranial compartments

The paper models CSF circulation to show that convection in the subarachnoid space rapidly clears tracers from intracranial compartments, reducing clearance time from years to days compared to diffusion.