Developmental Dysregulation of Synaptic and Myelin-Related Genes in Frontal Cortex and Serum Infrared Spectroscopy Signature in the Valproic Acid Model of Autism
Carolina Araújo, José Eduardo Kroll, Juliana Alves Brandão, Sérgio Ruschi, Camilo L. M. Morais, Marfran C. D. Santos, Rafael dos Santos Bessa, Kássio M. G. Lima, SANDRO JOSÉ DE SOUZA, Rodrigo Neves Romcy-Pereira
This study investigates molecular changes in the frontal cortex and serum of VPA-exposed rats, finding dysregulated myelin and synaptic genes and a serum FTIR spectroscopy biomarker for autism.
bioRxiv · Oct 4, 2025 · PreprintNeuroscience