Author

Jonathan M. Locke

University of ExeterORCID 0000-0001-9516-5251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Andrew R. WoodiD· 2 shared Anna MurrayiD· 2 shared Jessica TyrrelliD· 2 shared Katherine S. RuthiD· 2 shared Michael N. WeedoniD· 2 shared Robin N. BeaumontiD· 2 shared Timothy M. FraylingiD· 2 shared Ben West· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Andrew R. WoodORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 25, 2022

Genomic insights into the mechanism of NK3R antagonists for treatment of menopausal vasomotor symptoms

Katherine S. Ruth, Robin N. Beaumont, Jonathan M. Locke…·Anna Murray

This paper identifies a genetic association between NK3R (TACR3) and menopausal vasomotor symptoms (VMS) using GWAS, while finding no link between rare NK3R variants and VMS despite the efficacy of NK3R antagonists.

DOI 10.1101/2022.05.25.22275501

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 6, 2017

A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

Timothy M. Frayling, Robin N. Beaumont, Samuel E. Jones…·Andrew R. Wood

A common FGF21 allele is associated with lower body fat in the lower body, higher blood pressure, and increased carbohydrate intake in a large human cohort.

3 citations

humanGWAS summary statistics

𝕏 PostBluesky