A Model-agnostic Computational Method for Discovering Gene-Phenotype Relationships and Inferring Gene Networks via in silico Gene Perturbation
Rastko Stojšin, Xiangning Chen, Zhongming Zhao
This paper introduces a model-agnostic method to discover gene-phenotype relationships and infer gene networks using in silico gene perturbation, showing improved prognostic performance over conventional biomarkers.
medRxiv · Feb 21, 2024 · PreprintGenetic & Genomic Medicine