Gang Ren

The paper identifies LCORL and STC2 variants associated with increased body size and growth rate in cattle and other domesticated animals through genetic analysis and mouse models.

cLoops2 provides a comprehensive tool for analyzing 3D chromatin interactions, including loop detection and annotation, with open-source code available on GitHub.

The paper investigates how CTCF knockdown affects genome-wide cell-to-cell variation using single-cell RNA-seq, finding increased expression noise and enrichment of transcription factor-related genes in CTCF-KD cells.