Author

Christopher P. Castro

University of MichiganORCID 0000-0001-9727-1357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan P. BoyleiD· 3 shared Adam G. DiehliD· 2 shared Babak A. MahjouriD· 1 shared Camille MummiD· 1 shared G.A. FarnumiD· 1 shared Jessica A. SwitzenbergiD· 1 shared Monica J. HolmesiD· 1 shared Ryan E. MillsiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenetics

Alan P. BoyleORCID

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3 papers

Recent·Most cited

LRphase: an efficient method for assigning haplotype identity to long reads

Monica J. Holmes, Babak A. Mahjour, Christopher P. Castro, G.A. Farnum, Adam G. Diehl, Alan P. Boyle

LRphase is a tool for phasing long sequencing reads using known haplotypes to assign haplotype identity to variants.

PLoS ONE · Mar 13, 2024Peer-reviewedBioinformatics

Challenges in screening for de novo noncoding variants contributing to genetically complex phenotypes

Christopher P. Castro, Adam G. Diehl, Alan P. Boyle

The paper investigates why studies fail to find associations between de novo noncoding variants and complex disorders like ASD, identifying annotation quality and variant reliability as key issues.

Human Genetics and Genomics Advances · May 20, 2023Peer-reviewedGenetics

Cas9 targeted enrichment of mobile elements using nanopore sequencing

Torrin L. McDonald, Weichen Zhou, Christopher P. Castro, Camille Mumm, Jessica A. Switzenberg, Ryan E. Mills, Alan P. Boyle

The paper uses Cas9 targeted nanopore sequencing to enrich and detect mobile elements in human genomes, identifying non-reference MEIs missed by existing methods.

Nature Communications · Jun 11, 2021Peer-reviewedGenetics