Comparison of double-stranded and single-stranded cfDNA library construction methods for targeted genome and methylation sequencing
Jianchao Zheng, Zhilong Li, Xiuqing Zhang, Hongyun Zhang, Shida Zhu, Jianlong Sun, Yuying Wang
This study compares two cfDNA library construction methods for targeted genome and methylation sequencing, finding dsLib better for mutation detection and ssLib better for methylation analysis.
bioRxiv · Jan 12, 2022 · PreprintMolecular Biology