GeneticsbioRxivPreprint
In silico integration of thousands of epigenetic datasets into 707 cell type regulatory annotations improves the trans-ethnic portability of polygenic risk scores
Tiffany Amariuta, Kazuyoshi Ishigaki, Hiroki Sugishita…·Soumya Raychaudhuri
The paper integrates thousands of epigenetic datasets into 707 cell-type regulatory annotations to improve the trans-ethnic portability of polygenic risk scores by prioritizing variants in IMPACT regulatory elements.
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