Author

Joshua L. Wetzel

Princeton UniversityORCID 0000-0001-9838-4345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

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Kaiqian ZhangiD· 1 shared Mona SinghiD· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperMolecular Biology

Kaiqian ZhangORCID

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1 paper

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Molecular BiologyGenome ResearchPeer-reviewedSep 1, 2022

Learning probabilistic protein-DNA recognition codes from DNA-binding specificities using structural mappings

Joshua L. Wetzel, Kaiqian Zhang, Mona Singh

This paper introduces rCLAMPS, a method to infer protein-DNA recognition codes from DNA-binding specificities, enabling prediction of TF specificities and mutation effects.

19 citations

DNA methylationChIP-seq

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