Author

Bindi S. Brook

University of NottinghamORCID 0000-0001-9883-4131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:human· 1

Frequent Co-Authors

Anna Maria PiccininiiD· 1 shared Christine Selhuber‐UnkeliD· 1 shared Daniel A. VaughaniD· 1 shared Etienne FarcotiD· 1 shared Hannah J. PybusiD· 1 shared Mischa ZelzeriD· 1 shared Reuben D. O’DeaiD· 1 shared Sophie Geiger· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

Anna Maria PiccininiORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 15, 2025

Model of integrin binding as a function of light-induced variations in forces exerted on cells via RGD-terminated, photoswitchable azobenzene surfaces

Daniel A. Vaughan, Sophie Geiger, Anna Maria Piccinini…·Bindi S. Brook

The paper develops a mathematical model to predict integrin-mediated cell adhesion strength on light-responsive biomaterials and simulates retraction curves under varying experimental conditions.

DOI 10.1101/2025.07.15.664514

statistical model

Systems BiologyMathematical Medicine and Biology A Journal of the IMAPeer-reviewedJun 7, 2023

A dynamical model of TGF-β activation in asthmatic airways

Hannah J. Pybus, Reuben D. O’Dea, Bindi S. Brook

This study develops a dynamical model of TGF-β activation in asthmatic airways, showing bistable states and how external stimuli can irreversibly shift the system from healthy to diseased states.

4 citations

humanstatistical model