Reuben D. O’Dea

The impact of placental structure on haemodynamics and fetal oxygen uptake

This study uses computational models to show that placental structure significantly affects maternal blood flow and fetal oxygen uptake, with the vein-to-artery ratio being a key determinant of placental efficiency.

Understanding the regulation of chronic wounds by tissue inhibitors of matrix metalloproteinases through mathematical modelling

The paper develops a mathematical model of wound healing dynamics to show that deregulated apoptosis and low TIMP production lead to chronic wounds, and that TIMP-containing hydrogels can reverse them.

A dynamical model of TGF-β activation in asthmatic airways

This study develops a dynamical model of TGF-β activation in asthmatic airways, showing bistable states and how external stimuli can irreversibly shift the system from healthy to diseased states.

Reinforcement Learning approaches to hippocampus-dependent flexible spatial navigation

This paper reviews reinforcement learning frameworks for modeling hippocampus-dependent spatial navigation in watermaze tasks, discussing their behavioral and neurobiological validity.