MTB-KB consolidates fragmented MTB research into a structured knowledgebase with a knowledge graph, enabling exploration of MTB-host interactions and treatment strategies.

DOI 10.1093/gpbjnl/qzag102

statistical modeldatabase / resource

𝕏 PostBluesky

GenomicsGenomics Proteomics & BioinformaticsPeer-reviewedOct 1, 2025

Mitochondrial Genome Variants and Nuclear Mitochondrial DNA Segments in 7331 Individuals from NyuWa and 1KGP

Yuanxin Wang, Jiajia Wang, Yanyan Li…·Shunmin He

This study analyzes mitochondrial DNA variants and nuclear mitochondrial DNA segments in 7331 individuals from NyuWa and 1KGP, identifying common and ultra-rare NUMTs and linking mtDNA variants to nuclear DNA variants.

1 citation

humanwhole-genome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintNov 19, 2024

The Pathogen Adaptation of HLA Alleles and the Correlation with Autoimmune Diseases based on the HLA Diversity Resource in the Han Chinese

Shuai Liu, Yanyan Li, Tingrui Song…·Shunmin He

The paper investigates HLA allele adaptation to pathogens and its correlation with autoimmune diseases in Han Chinese individuals, identifying specific alleles linked to both pathogen resistance and disease susceptibility.

DOI 10.1101/2024.11.19.24317546

humanstatistical model

𝕏 PostBluesky