Yiwei Niu

This study analyzes mitochondrial DNA variants and nuclear mitochondrial DNA segments in 7331 individuals from NyuWa and 1KGP, identifying common and ultra-rare NUMTs and linking mtDNA variants to nuclear DNA variants.

The paper investigates HLA allele adaptation to pathogens and its correlation with autoimmune diseases in Han Chinese individuals, identifying specific alleles linked to both pathogen resistance and disease susceptibility.

The paper presents the NyuWa genome resource, a Chinese population-specific reference panel built from deep whole genome sequencing, which improves imputation accuracy and identifies novel variants.

The paper reports a comprehensive map of 36,699 non-reference mobile element insertions (MEIs) from 5,675 human genomes and builds a database for public use.

Ennet identifies cancer-driving networks using somatic enhancer mutations, revealing known and novel networks across multiple cancer types.