GenomicsbioRxivPreprint
Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder
Aleena Francis, Yogesh Dwivedi
The paper identifies cell-type-specific lncRNA-mediated gene silencing and enhancer activities in MDD, linking them to disrupted neuron-glia interactions and Hippo signaling.
DOI 10.1101/2025.10.16.682876