Xuesong Wang

This paper introduces MorphDiff, a transcriptome-guided diffusion model that predicts cell morphology changes under perturbations and improves MOA identification.

scMinerva is an unsupervised graph learning framework for single-cell multi-omics analysis that outperforms existing methods with few labels and provides biomarkers for COVID-19 cell differentiation.

conST learns embeddings from gene expression, spatial neighbors, and histology via three-level contrastive learning, reaching adjusted Rand index 0.65 on spatialLIBD slice 151673, with GNNExplainer-based explanations.

This paper introduces a framework to align and integrate single-cell RNA-seq and ATAC-seq data, achieving higher accuracy than existing methods on both simulated and real data.