Author

Nimrat Grewal

Yale New Haven HospitalORCID 0000-0001-9981-8336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:proteomics· 1

Frequent Co-Authors

Connie R. BezzinaiD· 2 shared Julia HorjusiD· 2 shared Sean Joseph JurgensiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Connie R. BezzinaORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintOct 5, 2026

Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta

Julia Horjus, Sean Joseph Jurgens, Connie R. Bezzina, Nimrat Grewal

This study uses Mendelian randomization to assess the causal role of CACNA1C, a target of calcium channel blockers, on thoracic aortic aneurysm and dissection, finding lower risk with higher aortic expression.

DOI 10.64898/2026.10.02.26364570

humanDNA methylation

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Genetic & Genomic MedicinemedRxivPreprintAug 26, 2026

Transcriptomic and proteomic Mendelian randomization identifies putative therapeutic targets for thoracic aortic disease

Julia Horjus, Sean Joseph Jurgens, Connie R. Bezzina, Nimrat Grewal

This study uses Mendelian randomization to identify 28 putative causal genes for thoracic aortic disease, highlighting potential therapeutic targets.

1 citation

humanproteomics

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