Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics
Thomas De Luca, Robert E. Stratford, Madison E. Edwards, Christina Ramires Ferreira, Eric A. Benson
This paper introduces a method to quantify extracellular vesicles in vivo without modifying surface ligands, using an oligonucleotide tracer and droplet digital PCR, and applies it to study kinetic differences between EVs from different cell types.
bioRxiv · Sep 22, 2020 · PreprintMolecular Biology