Comprehensive epigenomic profiling of human alveolar epithelial differentiation identifies key epigenetic states and transcription factor co-regulatory networks for maintenance of distal lung identity
Beiyun Zhou, Theresa Ryan Stueve, E. A. Mihalakakos, Lin Miao, Daniel J. Mullen, Y Wang, Y. Liu, Jinli Luo, Evelyn Tran, Kim D. Siegmund, Sean K. Lynch, Amy L. Ryan, Ite A. Laird‐Offringa, Zea Borok, Crystal N. Marconett
This study identifies key epigenetic states and transcription factor networks in human alveolar epithelial differentiation, revealing dynamic enhancer changes and regulatory interactions critical for distal lung identity.
BMC Genomics · Dec 1, 2021Peer-reviewedGenomics