Daniel J. Mullen

Immunizing small cell lung cancer mice with isoaspartylated Elavl4 after chemotherapy mimics improved survival of anti-ELAVL4 antibody-positive small cell lung cancer patients

This study shows that immunizing SCLC mice with isoaspartylated Elavl4 after chemotherapy improves survival, mirroring the benefit seen in patients with anti-ELAVL4 antibodies.

Comprehensive epigenomic profiling of human alveolar epithelial differentiation identifies key epigenetic states and transcription factor co-regulatory networks for maintenance of distal lung identity

This study identifies key epigenetic states and transcription factor networks in human alveolar epithelial differentiation, revealing dynamic enhancer changes and regulatory interactions critical for distal lung identity.