Peng Xie

This paper constructs sex-specific lifespan brain charts using neuroimaging data from 59,915 individuals, revealing dynamic sex differences in brain development and improving detection of neuropsychiatric abnormalities.

This study shows Sephin1 protects oligodendrocytes and reduces white matter injury after intracerebral hemorrhage by inhibiting apoptosis and neuroinflammation.

The paper develops population-specific brain charts for Chinese individuals, revealing distinct neurodevelopmental patterns compared to Western populations and showing better performance in predicting brain phenotypes.

The paper analyzes functional and structural MRI data from 33,250 individuals to map lifespan changes in the functional connectome, identifying key developmental stages and differences in neurological disorders.

This study identifies dysfunction in the principal connectome gradient in MDD and links it to gene expression profiles related to transsynaptic signaling and calcium ion binding.

The paper analyzes resting-state fMRI data from 1,300 MDD patients and 1,128 controls to find reduced default mode network functional connectivity in recurrent MDD, not first-episode MDD.

This study investigates reproducibility of functional brain alterations in MDD using a large multisite R-fMRI dataset and finds consistent patterns across centers but notes influences from clinical factors.